In a significant stride toward developing more effective treatments for aggressive cancers, researchers from Oak Ridge National Laboratory (ORNL) have achieved remarkable insights into the workings of the enzyme serine hydroxymethyltransferase (SHMT). Utilizing neutron experiments, the team uncovered detailed atomic interactions within this crucial metabolic enzyme, instrumental in cell division and cancer proliferation. This innovative
Chemistry
Hydrogen gas is increasingly being recognized as a cornerstone in the quest for sustainable and carbon-free energy solutions. Renowned for its high energy density, hydrogen presents a tantalizing opportunity for the future of eco-friendly energy. Despite its status as the universe’s most plentiful element, hydrogen primarily exists in bound forms within compounds like ammonia and
The prevalence of pharmaceutical contaminants in water supplies has become a significant environmental concern. As populations grow and urban areas expand, municipal wastewater systems struggle with the accumulation of various drugs, including antibiotics, synthetic hormones, and anti-inflammatory medications. Research conducted by scientists from Carnegie Mellon University reveals that these micropollutants not only permeate wastewater treatment
The 2023 Nobel Prize in Chemistry has been awarded to three remarkable scientists who have significantly contributed to our understanding of proteins, the fundamental molecules essential for life. Demis Hassabis and John Jumper from Google’s DeepMind leveraged the potential of artificial intelligence (AI) to predict protein structures, while biochemist David Baker innovatively designed proteins that
The image of a figure soaring above city streets, propelled by strands of webbing, is one that captures the imagination of countless children (and adults) raised on comic books and superhero films. The scientific community is now taking this whimsy seriously, as researchers at Tufts University have unveiled an innovative technology that allows for the
Covalent bonds are fundamental to the structure of organic molecules, comprising the mainstay of chemical interactions that define life as we know it. Traditionally, these bonds involve the sharing of electron pairs between atoms, allowing a myriad of compounds to form. However, the exploration of alternative bonding mechanisms has led researchers to consider more complex
The fashion industry is notorious for its environmental impact, with millions of tons of clothing ending up in landfills each year. However, groundbreaking research from Cornell University is championing a new approach to sustainability, unveiling a technique to create waterproof coatings from discarded textiles. This innovative method, directed by Professor Juan Hinestroza and his team,
The realm of organic chemistry has long been overshadowed by the challenge of activating alkanes, compounds that are foundational to many industrial applications, including pharmaceuticals and materials production. Recent research from Hokkaido University in Japan has unveiled an unprecedented method to transform these stable hydrocarbons into more reactive and useful compounds. This advancement not only
Nitrogen oxides (NOx), which primarily include nitric oxide (NO) and nitrous oxide (N2O), are pollutants released largely from industrial processes, including fertilizer manufacturing. The concern surrounding these gases extends beyond their immediate toxicity; they are significant contributors to environmental degradation. Nitric oxide is a precursor to acid rain, while nitrous oxide poses a dire climate
Recent scientific advancements have unveiled an intriguing insight into the behaviors of barnacles, a marine organism that strategically cleans surfaces prior to adhering with their biologically produced “glue.” Researchers, particularly from Northeastern University, have taken inspiration from this natural process to explore innovative methods to tackle biofilms—complex communities of microorganisms that can pose significant challenges
Plastic pollution has reached alarming levels globally, affecting ecosystems from the ocean depths to the soil beneath our feet. Each year, an astounding 368 million metric tons of plastics are produced, a significant portion of which finds its way into various environmental compartments. Of this, over 13 million metric tons are estimated to settle in
The field of medicinal chemistry is set to undergo transformative changes thanks to groundbreaking research from a team led by a chemist at the University of Texas at Dallas (UT Dallas). This research introduces a novel chemical reaction that allows scientists to selectively synthesize either left-handed or right-handed enantiomers—commonly referred to as mirror molecules—affecting their
A groundbreaking study led by Professor Jaeheung Cho at UNIST has unveiled critical insights regarding cobalt(III)-based metal complexes and their interactions with nitriles. These findings, recently published in the prestigious Journal of the American Chemical Society, set a compelling foundation for future advancements in drug development. By illuminating the intricate mechanism of nitrile activation through
In the quest for sustainable chemical synthesis, chemists have sought alternatives to traditional catalyst systems, particularly those reliant on biological proteins. Researchers at the National University of Singapore (NUS) have emerged as pioneers in this domain, introducing a groundbreaking method that merges DNA repair mechanisms with biorthogonal chemistry to create a versatile platform for producing
The conversion of carbon dioxide (CO2) into useful chemicals remains a critical area of research, particularly in the context of climate change and sustainable energy solutions. Electrochemical reduction processes promise a revolutionary method of carbon utilization, transforming CO2 into valuable products. Historically, the focus has primarily been on refining the catalysts for these reactions. However,
In the rapidly evolving field of battery technology, lithium and sodium metal anodes have emerged as key contenders in the quest for high-performance solid-state batteries. Solid-state batteries promise enhanced safety, energy density, and longevity, positioning them as a potential replacement for conventional lithium-ion batteries. However, the performance and stability of these batteries heavily hinge on